Introduction:

In the Health Services and in Local Governments, where a number of authorities have banned the use of liquid chlorine bleach, NaDCC Sodium Dichloroisocyanurate Granules and Tablet formulations predominate as the favoured method of Chlorine Disinfection. Disinfecting solutions prepared from Akrosept Effervescent Chlorine Tablets & Granules are fast acting and have a complete spectrum of Biocidal Activity. Bacteria, Bacterial Spores, Algae, Fungi, Protozoa and Viruses are sensitive to their effects.

With the advent of the Health and Safety Act, COSHH (the Control of Substances Hazardous to Health Regulations) and CHIP (the Chemicals Hazard Information and Packaging for Supply Regulations), there has been a move towards safer handling and use of chemicals.

One of the greatest offenders involved in accidents both in the workplace and in the hospitals is liquid chlorine bleach, or Sodium Hypochlorite (NaOCL). Liquid Chlorine Bleach is responsible for thousands of accidents a year but is still widely used out of all disinfectants. This is because chlorine (of which bleach is just one of a number of donors) is regarded by many, including the Health Service and the Government, as the most effective disinfectant in the fight against disease. That is why it is recommended by the world’s major authorities for use against HIV (AIDS) and Hepatitis B viruses and why almost all of the world’s piped supplies are treated with chlorine.

Unfortunately, liquid chlorine bleach has a number of inherent disadvantages:

1. It is unstable and degrades with age. In adverse storage conditions, the rate of degradation accelerates until the active strength disappears.
2. It is corrosive and can damage the skin and eyes of the operator.
3. It bleaches, stains and rots clothing and soft fabrics.
4. It is difficult to handle and store, and requires venting caps which make spillage more likely.
5. The strengths available vary so widely that it is difficult to make up accurate in-use solutions.

The use of chlorine products for infection control has a long and successful history in the medical arena. The earliest records date back to the 18^th Century, when chlorine gas was used for fumigation in hospitals. But it was in the mid to late 19^th Century when chlorine became pre-eminent as a hospital disinfectant, and its wide use continues today. 

Akrosept Disinfectant Tablets & Granules provide today’s answer, with their superior activity over traditional hypochlorite’s, coupled with their safe and simple application.

The term Disinfection is applied to a chemical agent which destroys or inhibits the growth of pathogenic microorganisms in the non-sporing or vegetative state. Disinfectants do not necessarily kill all microorganisms, but reduce them to a level that is harmful to neither health nor the quality of perishable goods. The term is used for agents used to treat inanimate objects and materials, and may also be applied to agents used to treat the skin and other body membranes and cavities.

• High-Level Disinfectants can be expected to destroy all microorganisms, with the exception of high numbers of spores.
• Intermediate-Level Disinfectants inactivate mycobacterium tuberculosis, vegetative bacteria, most viruses, and most fungi, but do not necessarily kill bacterial spores.
• Low-Level Disinfectants can kill most bacteria, some viruses, and some fungi, but cannot be relied on to kill resistant microorganisms such as tubercule bacilli or bacterial spores.

Akrosept Disinfectant Tablets & Granules can reasonably be deduced to have a wide spectrum disinfectant effect, which is suitable for use for High, Intermediate and Low-Level Disinfection.

Akrosept Disinfectant Tablets - are effervescent disinfectant tablets which, when added to water, release disinfectant solutions at known and reliable in-use strengths. The tablet utilise the ingredient Sodium Dichloroisocyanurate (NaDCC), which is an organic chlorine donor that releases the active compound Hypochlorous Acid. NaDCC Sodium Dichloroisocyanurate is not a hypochlorite. NaDCC Sodium Dichloroisocyanurate dissolves in water to release Hypochlorous Acid (HOCL) and Monosodiumcyanurate.

Akrosept Disinfectant Granules - are effervescent disinfection granules containing the active ingredient Soduim Dichloroisocyanurate. They react with water in blood spillages to produce a rapid acting, wide spectrum disinfectant effective against vegetative bacteria, fungi, viruses and bacterial spores.

Its chemistry and mode of action in solution is significantly different than hypochlorite, giving an activity that is substantially more effective than hypochlorite, particularly where there may be organic contamination

They are Proven, Practical & Convenient Approach to Hard-Surface Disinfection.

Akrosept Tablets & Granules dissolve rapidly in water to produce a rapid acting, wide spectrum disinfectant solution effective against:

• Vegetative Bacteria
• Fungi
• Viruses
• Bacterial Spores including Tubercle bacilli, HBV, HIV, Hepatitis B and Herpes Virus

Advantages of using Akrosept Tablets & Granules:

• Akrosept Tablets & Granules take hard surface disinfection beyond the confines of hypochlorites. A complete biocidal spectrum based on the unique action of NaDCC Sodium Dichloroisocyanurate ensures highly effective disinfection even in the presence of blood or other organic matter.
• Akrosept  Tablets & Granules have demonstrable wide spectrum activity, verified for high, intermediate and low-level disinfection.
• Akrosept Tablets & Granules are highly effective in Infection Control.
• With long term stability in storage, full activity is guaranteed right up to the moment of use. In every Hospital/Nursing Home, Akrosept Tablets & Granules provide a practical, convenient and rational approach to disinfection.
• Akrosept Tablets & Granules provide better activity in the presence of organic matter than hypochlorites and may be used with confidence for all body fluid spillages. They provide better resistance to organic solids than hypochlorites.
• Akrosept Tablets & Granules provide better biocidal activity than hypochlorites.
• Akrosept Tablets & Granules are stable and compact in storage, ensuring full biocidal activity up to the moment of use. They are safe, simple and provide accurate preparation.
• Akrosept Tablets & Granules are convenient, reliable, economical & easy to use for the staff.
• Akrosept Tablets & Granules take up little storage space, when compared to liquids. They do not spill or leak, and are safe and easy to transport.
• Akrosept Tablets & Granules are compatible with certain detergents.

• Akrosept  Tablets & Granules provide Rapid Action
• Akrosept Tablets & Granules are stable and have a long shelf life of 24 Months.
• Akrosept Tablets & Granules are accurate, always yielding the stated level of available chlorine.
• Akrosept Tablets & Granules are convenient and easy to use. Just add to water and allow to dissolve. The speed of dissolution can be enhanced by use of warm water and/or by stirring.
• Akrosept Tablets & Granules are Economical in use. They provide an easy to use dilution system that eradicates the over-dosing that is common in liquid bleach and more importantly minimizes any under-dosing potential.
• Akrosept Tablets & Granules are easy to store and distribute. No spillages, no leaks.
• Akrosept Tablets & Granules are much safer to use than Liquid Chlorine Bleach, which means reduced risk of accident and personal injury.
• Akrosept Tablets & Granules are less corrosive than liquid chlorine bleach. Tests have shown that nearly all metals in common use are more readily corroded by liquid chlorine bleach than Akrosept Tablets or Granules.
• Akrosept Tablets & Granules possess greater biocidal properties, strength for strength than liquid chlorine bleach especially in the presence of soiling.
• Akrosept Tablets & Granules dissolve in solution to a near pH solution of 6.2 which means maximum antimicrobial activity at a minimum concentration of Cl & safer for operatives, unlike Sodium Hypochlorite which is invariably pH 9.0 – 12.9.
• Akrosept Tablets & Granules are proven to be more effective in reducing Bacteria Total Plate Count (TPC) than solutions made using Sodium Hypochlorite Liquid Chlorine Bleach.
• Solution prepared from Akrosept Tablets & Granules is stable for 24 hours.
• Akrosept Tablets & Granules produce rapid acting, wide spectrum disinfectant solution effective against Mycobacteria & Bacteria, Fungi, Viruses, Bacterial Spores. Hence they are Tuberculocidal, Bactericidal, Virucidal, Fungicidal, and Sporicidal.
• Akrosept Tablets & Granules give better resistance to organic soils than Hypochlorites.
• Akrosept Tablets & Granules give superior activity in presence of organic material.
• Solution prepared from Akrosept ensures better solutions for disinfection activity across the microbial spectrum, providing protection against many organisms including HIV, Hepatitis B, Herpes viruses and MRSA
• Akrosept’s active ingredient NaDCC Sodium Dichloroisocyanurate is a slow dissociate and connected by proteins.

Dilution and Usage/Application of Akrosept Tablets:

For Akrosept 500 mg: Dissolve One tablet in 2 Litres of Water to prepare Powerful Disinfectant Solution containing 140 PPM of Available Chlorine Strength.

For Akrosept 2500 mg: Dissolve One tablet in 10 Litres of Water to prepare Powerful Disinfectant Solution containing 140 PPM of Available Chlorine Strength.

For Akrosept 5000 mg: Dissolve One tablet in 20 Litres of Water to prepare Powerful Disinfectant Solution containing 140 PPM of Available Chlorine Strength.

Solution prepared from Akrosept Tablets/Granules is suitable for disinfection of:

• General Environment
• Working/Hard Surfaces
• Floors
• Walls
• Furniture, Cupboards, Tables
• Baby Bottles, Toys
• Door Knobs, Handles, Switches
• Utensils, Cutlery, Crockery, Kitchen, Kitchen Sponge
• Glasswares, Stainless Steel Instruments
• Instruments/Equipments/Disposables in; All Hospital Departments, Maternity Units (Disinfection of Baby Bottles and Feeding Utensils), Nurseries, Intensive Care, Laboratories, Surgeries together with General Hospital Disinfection.
• Cleaning Operation Theater, Emergency Wards, Surgical Wards
• Washing of Hands, Gloves & Other Daily Use Articles
• Sterilizing of Clothes bedding, bed sheets, linens, pillow covers & towels used by Hospitals.
• Mobile Phones, Gadgets, Appliances
• Sink, Wash Basin, Soap Dispenser, Lavatory, Toilet, Bucket, Urinal, Sponge

Should be used at:

Hospitals, Nursing Homes, Clinics, Laboratories, Homes, Workplace, Offices, Shops, Factories, Showrooms, Malls, Schools, Police Stations, Old Age Homes, Large Gathering Areas, Religious Establishments etc.

Directions For Use of Akrosept Tablets:

1. Dilution: Select the required number of tablets to prepare the required strength of Akrosept Solution by referring to the Dilution Instruction Chart. All solutions should be prepared fresh daily. Solution is active for 24 Hours.
2. Pre-cleaning: All objects should be thoroughly pre-cleaned prior to disinfection. Thoroughly rinse with water and rough dry objects before immersing in Akrosept Solution.
3. Disinfection: Note: Confirm the object’s compatibility with Akrosept Solution prior to use. Immerse the object fully in the Akrosept Solution and ensure that all surfaces and lumens are in contact with the Solution. Adhere to contact time. For disinfection of surfaces, ensure that Akrosept Solution contacts the entire surface.
4. Rinsing: All disinfected items should be thoroughly rinsed with water of suitable quality in order to remove the remaining Akrosept Solution. The rinse water should be discarded after use and not reused for any other purpose. Rough dry.

Directions For Use of Akrosept Granules:

1. Use for the safe containment and neutralization of body fluid spillages.
2. Simply sprinkle Akrosept Granules onto the spillage and leave approximately 2 minutes.
3. Once the spillage has been soaked up, use a disposable cloth and clear the area. Rinse with clean water.

Storage of Akrosept Tablets & Granules:

• Store in original container in a cool dry place below 25^o in the Original Container.
• Store at controlled room temperature and in a well ventilated area.
• Store out of direct sunlight.
• Replace cap firmly between uses.
• Use all tablets within 1 month of opening of bottle.
• The expiry date of Akrosept is marked on the container.

Safety for the staff while using Akrosept Tablets & Granules:

• Follow the instructions for use and safety data sheet.
• Ensure that there is no dilution from concentrate for example thick bleach.
• Personal Protective Equipment (PPE) should be worn & used while handling Akrosept Tablets and Solution prepared from them.
• Gloves and Safety Goggles should be used while making dilution.
• Gloves should be used while its usage on surfaces.

Caution while using Akrosept Tablets & Granules:

• Not to be taken internally.
• Keep out of reach of children.
• Avoid contact with skin and eyes. Incase of eye contact, irrigate with copious amount of water.

Akrosept & Environment:

• Dispose used Akrosept Solution to drain or as per Hospital Policy
• Akrosept Solution will degrade in the environment through Chemical Activity

Composition of Akrosept Tablets:

Akrosept comes in 3 different strengths:

• Akrosept Tablet containing NaDCC Sodium Dichloroisocyanurate 500mg or   0.5 gm
• Akrosept Tablet containing NaDCC Sodium Dichloroisocyanurate 2500mg or 2.5 gm
• Akrosept Tablet containing NaDCC Sodium Dichloroisocyanurate 5000mg or 5.0 gm

Packing of Akrosept Tablets:

For Akrosept Tablet containing NaDCC Sodium Dichloroisocyanurate 500mg or 0.5 gm

• 50/100/250/500/1000 Tablets of 500mg each packed in a Plastic Container/Bottle

For Akrosept Tablet containing NaDCC Sodium Dichloroisocyanurate 2500mg or 2.5 gm

• 50/100/200 Tablets of 2500mg each packed in a Plastic Container/Bottle

For Akrosept Tablet containing NaDCC Sodium Dichloroisocyanurate 5000mg or 5.0 gm

• 50/100/200 Tablets of 5000mg each packed in a Plastic Container/Bottle

Packing of Akrosept Granules:

• 500 gm / 1 Kg / 2 Kgs/ 5 Kgs packed in a Plastic Container/Bottle.

Dilution Instructions for Akrosept Disinfection Tablets

Disinfection Of	Required Concentration Of Available Chlorine	Dilution Rates		Additional Instructions
		0.5 gm Tablets	2.5gm Tablets
Blood Spillage+	10,000 PPM	18 Tablets in 0.5 Litre water	7 Tablets in 1 Litre water	Pour over blood using gloves. Wipe up with disinfectant saturated disposal cloth.
Pipette Jars+	2,500 PPM	9 Tablets in 1 Litre water	9 Tablets in 5 Litres water	Drop Tablets into water filled pipette jar. Discard daily.
General Laboratory/ Environmental Use+	1,000 PPM	4 Tablets in 1 Litre water	4 Tablets in 5 Litres water	Wipe down surfaces with disposal disinfectant saturated disposal cloth.
Stainless Steel Instruments	560 PPM	1 Tablet in 0.5 Litre water	1 Tablet in 2.5 Litres water	Immerse  for 1 hour.
Baby Bottles/Teats, Stainless Steel Utensils, Porcelain, Glassware, Rubber and Plastic Tubing	140 PPM	1 Tablet in 2 Litres water	1 Tablet in 10 Litres water	Immerse for 1 hour.
Eating Utensils and Crockery	140 PPM	1 Tablet in 2 Litres water	1 Tablet in 10 Litres water	Rinse for 1-2 minutes.
Soiled or Infected Linen	140 PPM	1 Tablet in 2 Litres water	1 Tablet in 10 Litres water	Immerse for 1 hour prior to washing.
Work Surfaces, Cupboards, Floors, etc.	140 PPM	1 Tablet in 2 Litres water	1 Tablet in 10 Litres water	Wash Down.
Dishcloths, Mops, etc.	60 PPM	1 Tablet in 4.6 Litres water	1 Tablet in 23 Litres water	Soak to Bleach Clean and Deodorize